Abstract: Recent advances in spatial transcriptomics have enabled the comprehensive measurement of transcriptional profiles while retaining the spatial contextual information. Identifying spatial ...

Spatial biology is a rapidly advancing discipline that examines biological molecules (such as DNA, RNA, and proteins) within their native locations in tissues. This approach offers critical insight ...

Graph Convolutional Networks (GCNs) are widely applied for spatial domain identification in spatial transcriptomics (ST), where node representations are learned by aggregating information from ...

Artificial intelligence (AI) has become a common tool for bioinformatics, with hundreds of methods published in recent years. Due to the training data demands of deep-learning algorithms, ...

Single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics are revolutionary techniques that offer unparalleled insights into cellular function and tissue architecture. scRNA-seq allows ...

This study addresses a critical challenge in spatial multi-omics: the effective integration of heterogeneous molecular modalities within complex tissue environments. By introducing SpaDDM, a ...

The field of spatial transcriptomics utilizes technologies that map gene expression data to specific cellular locations within tissues. While traditional RNA sequencing methods generate quantitative ...

This repository contains the code of the paper "DeepSpot: Leveraging Spatial Context for Enhanced Spatial Transcriptomics Prediction from H&E Images". Authors: Kalin Nonchev, Sebastian Dawo, Karina ...

Abstract: The majority of spatial transcriptomics datasets are characterized by low resolution, wherein each spot generally encompasses multiple cells. This limitation poses challenges for exploring ...

Applying single-cell RNA sequencing has led researchers to be able to profile the entire transcriptome of cells. However, these transcriptomes prove difficult to link back to their original location ...

Spatial audio is having a moment. While the goal of offering a more immersive, 3D-like listening experience may have been born in movie theaters, much of the conversation around spatial audio has ...